Revisão Acesso aberto Produção Nacional Revisado por pares

Vaccines for COVID-19: perspectives from nucleic acid vaccines to BCG as delivery vector system

2020; Elsevier BV; Volume: 22; Issue: 10 Linguagem: Inglês

10.1016/j.micinf.2020.09.004

ISSN

1769-714X

Autores

Nina Marí Gual Pimenta de Queiroz, Fábio V. Marinho, Marcelo Chagas, Luciana C. C. Leite, E. Jane Homan, Mariana T. Q. de Magalhães, Sérgio C. Oliveira,

Tópico(s)

COVID-19 Clinical Research Studies

Resumo

This article discusses standard and new disruptive strategies in the race to develop an anti-COVID-19 vaccine. We also included new bioinformatic data from our group mapping immunodominant epitopes and structural analysis of the spike protein. Another innovative approach reviewed here is the use of BCG vaccine as priming strategy and/or delivery system expressing SARS-CoV-2 antigens.

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