
Vaccines for COVID-19: perspectives from nucleic acid vaccines to BCG as delivery vector system
2020; Elsevier BV; Volume: 22; Issue: 10 Linguagem: Inglês
10.1016/j.micinf.2020.09.004
ISSN1769-714X
AutoresNina Marí Gual Pimenta de Queiroz, Fábio V. Marinho, Marcelo Chagas, Luciana C. C. Leite, E. Jane Homan, Mariana T. Q. de Magalhães, Sérgio C. Oliveira,
Tópico(s)COVID-19 Clinical Research Studies
ResumoThis article discusses standard and new disruptive strategies in the race to develop an anti-COVID-19 vaccine. We also included new bioinformatic data from our group mapping immunodominant epitopes and structural analysis of the spike protein. Another innovative approach reviewed here is the use of BCG vaccine as priming strategy and/or delivery system expressing SARS-CoV-2 antigens.
Referência(s)