Extracellular Vesicle Biogenesis and Functions in Gram-Positive Bacteria
2020; American Society for Microbiology; Volume: 88; Issue: 12 Linguagem: Inglês
10.1128/iai.00433-20
ISSN1098-5522
AutoresPaul Briaud, Ronan K. Carroll,
Tópico(s)Infective Endocarditis Diagnosis and Management
ResumoExtracellular vesicles (EVs) are membrane-derived lipid bilayers secreted by bacteria and eukaryotic cells. Bacterial membrane vesicles were discovered over 60 years ago and have been extensively studied in Gram-negative bacteria. During their production, EVs are loaded with proteins, nucleic acids, and various compounds that are subsequently released into the environment. Depending on the packaged cargo, EVs have a broad spectrum of action and are involved in pathogenesis, antibiotic resistance, nutrient uptake, and nucleic acid transfer.
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