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High-resolution metabolic imaging of high-grade gliomas using 7T-CRT-FID-MRSI

2020; Elsevier BV; Volume: 28; Linguagem: Inglês

10.1016/j.nicl.2020.102433

2213-1582

Gilbert Hangel, Cornelius Cadrien, Philipp Lazen, Julia Furtner, Alexandra Lipka, Eva Hečková, Lukas Hingerl, Stanislav Motyka, Stephan Gruber, Bernhard Strasser, Barbara Kiesel, Mario Mischkulnig, Matthias Preusser, Thomas Roetzer, Adelheid Wöhrer, Georg Widhalm, Karl Rössler, Siegfried Trattnig, Wolfgang Bogner,

Glioma Diagnosis and Treatment

Successful neurosurgical intervention in gliomas depends on the precision of the preoperative definition of the tumor and its margins since a safe maximum resection translates into a better patient outcome. Metabolic high-resolution imaging might result in improved presurgical tumor characterization, and thus optimized glioma resection. To this end, we validated the performance of a fast high-resolution whole-brain 3D-magnetic resonance spectroscopic imaging (MRSI) method at 7T in a patient cohort of 23 high-grade gliomas (HGG).