Artigo Acesso aberto Revisado por pares

UV-initiated crosslinking of electrospun chitosan/poly(ethylene oxide) nanofibers doped with ZnO-nanoparticles: development of antibacterial nanofibrous hydrogel

2020; Springer Nature; Volume: 10; Issue: 4 Linguagem: Inglês

10.1557/mrc.2020.74

ISSN

2159-6859

Autores

G. M. Estrada-Villegas, José Ignacio Del Río de Vicente, Liliana Argueta‐Figueroa, Giovanni González-Pérez,

Tópico(s)

Advanced Sensor and Energy Harvesting Materials

Resumo

UV-initiated crosslinking of electrospun poly(ethylene) oxide (PEO)/chitosan (CS) nanofibers doped with zinc oxide nanoparticles (ZnO-NPs) was performed using pentaerythritol triaclyrate (PETA) as the photoinitiator and crosslinker agent. The influence of the addition of PETA to the PEO/CS diameter and crosslinking of nanofibers was evaluated. The effect of irradiation time on the morphology and swelling properties of the crosslinked nanofibers were investigated. For ZnO-NPs, the minimum inhibitory concentrations were found at 1 mg/mL, and the minimum bactericidal concentrations at 2 mg/mL for all the strains tested. The nanofibrous hydrogel antibacterial effect was tested. This material enters the realm of fibrous hydrogels which have potential use in several applications as in the biomedical area.The supplementary material for this article can be found at 10.1557/mrc.2020.74.

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