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Accounting for individual variability in baseline seizure frequencies when planning randomized clinical trials remains challenging

2020; Wiley; Volume: 61; Issue: 10 Linguagem: Inglês

10.1111/epi.16676

1528-1167

Georg Zimmermann, Eugen Trinka,

Statistical Methods in Clinical Trials

EpilepsiaVolume 61, Issue 10 p. 2321-2322 LETTER Accounting for individual variability in baseline seizure frequencies when planning randomized clinical trials remains challenging Georg Zimmermann, Corresponding Author Georg Zimmermann georg.zimmermann@pmu.ac.at orcid.org/0000-0002-8282-1034 Team Biostatistics and Big Medical Data, IDA Lab Salzburg, Paracelsus Medical University, Salzburg, Austria Department of Neurology, Christian Doppler University Hospital, Paracelsus Medical University, Salzburg, Austria Department of Mathematics, Paris-Lodron-University of Salzburg, Salzburg, Austria Correspondence Georg Zimmermann, Team Biostatistics and Big Medical Data, IDA Lab Salzburg, Paracelsus Medical University, Strubergasse 16, A-5020 Salzburg, Austria. Email: georg.zimmermann@pmu.ac.atSearch for more papers by this authorEugen Trinka, Eugen Trinka orcid.org/0000-0002-5950-2692 Department of Neurology, Christian Doppler University Hospital, Paracelsus Medical University, Salzburg, Austria Center for Cognitive Neuroscience, Salzburg, Austria Department of Public Health, Health Services Research and Health Technology Assessment, University for Health Sciences, Medical Informatics, and Technology, Hall in Tirol, AustriaSearch for more papers by this author Georg Zimmermann, Corresponding Author Georg Zimmermann georg.zimmermann@pmu.ac.at orcid.org/0000-0002-8282-1034 Team Biostatistics and Big Medical Data, IDA Lab Salzburg, Paracelsus Medical University, Salzburg, Austria Department of Neurology, Christian Doppler University Hospital, Paracelsus Medical University, Salzburg, Austria Department of Mathematics, Paris-Lodron-University of Salzburg, Salzburg, Austria Correspondence Georg Zimmermann, Team Biostatistics and Big Medical Data, IDA Lab Salzburg, Paracelsus Medical University, Strubergasse 16, A-5020 Salzburg, Austria. Email: georg.zimmermann@pmu.ac.atSearch for more papers by this authorEugen Trinka, Eugen Trinka orcid.org/0000-0002-5950-2692 Department of Neurology, Christian Doppler University Hospital, Paracelsus Medical University, Salzburg, Austria Center for Cognitive Neuroscience, Salzburg, Austria Department of Public Health, Health Services Research and Health Technology Assessment, University for Health Sciences, Medical Informatics, and Technology, Hall in Tirol, AustriaSearch for more papers by this author First published: 30 September 2020 https://doi.org/10.1111/epi.16676Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article. Volume61, Issue10October 2020Pages 2321-2322 RelatedInformation