Artigo Acesso aberto Revisado por pares

Consenso colombiano para la prevención, el diagnóstico y el tratamiento de condiciones trombóticas en adultos con COVID-19: aplicando el Marco de la Evidencia a la Decisión (EtD) GRADE

2020; Elsevier BV; Volume: 27; Issue: 5 Linguagem: Inglês

10.1016/j.rccar.2020.08.003

ISSN

2357-3260

Autores

Juan Acevedo-Peña, Nancy Yomayusa-González, Francy Cantor-Cruz, Carlos Eduardo Pinzón-Flórez, Liliana Barrero-Garzón, Ilich Herbert De La Hoz Siegler, Eduardo Low-Padilla, Carlos Ramírez-Cerón, Juan Felipe Combariza, Carlos Andrés Arias-Barrera, Javier Moreno-Cortés, José M. Rozo-Vanstrahlen, Liliana Correa, José Antonio Rojas-Gambasica, Camilo González, Eduardo La-Rotta-Caballero, Paula Ruíz-Talero, Rubén Contreras-Páez, Alberto Lineros-Montañez, Jorge Ordoñez-Cardales, Mario Escobar-Olaya, Raúl Izaguirre-Ávila, Joao Campos-Guerra, José Accini-Mendoza, Camilo Pizarro-Gómez, Adulkarín Patiño-Pérez, Janine Flores-Rodríguez, Albert Valencia-Moreno, Alejandro Londoño-Villegas, Alfredo Saavedra-Rodríguez, Ana Madera-Rojas, Andrés Caballero-Arteaga, Andrés Díaz-Campos, Felipe Correa-Rivera, Andrés Mantilla-Reinaud, Ángela Becerra-Torres, Ángela Peña-Castellanos, Aura Reina-Soler, Bibiana Escobar, Bonell Patiño-Escobar, Camilo Rodríguez-Cortés, Carlos Rebolledo-Maldonado, Carlos Ocampo-Botero, Carlos Rivera-Ordoñez, Carlos H. Saavedra-Trujillo, Catalina Figueroa-Restrepo, Claudia Agudelo-López, Claudia Jaramillo-Villegas, C. Villaquirán-Torres, Daniel Rodríguez-Ariza, David A. Rincón‐Valenzuela, Melissa Lemus-Rojas, Diego Alejandro Pinto, Diego Garzón-Díaz, Diego Cubillos-Apolinar, Edgar Beltrán-Linares, Emilio Kondo-Rodríguez, Erica Yama-Mosquera, Ernesto Polania-Fierro, Evalo Real-Urbina, Andrés Rosas-Romero, Fernán Mendoza-Beltrán, Freddy Guevara, Gina Celia-Márquez, Gloria Ramos-Ramos, Gonzalo Prada-Martínez, Guillermo León-Basantes, Guillermo Liévano-Sánchez, Guillermo Ortíz, Gustavo Barreto-García, Harold Ibagón-Nieto, Henry Idrobo‐Quintero, Ingrid Martínez-Ramírez, Ivan Solarte-Rodríguez, Jorge Quintero-Barrios, Jaime Arenas-Gamboa, Jairo Pérez-Cely, Jeffrey Castellanos-Parada, Fredy Garzón-Martínez, Joaquín Gustavo Luna-Ríos, Joffre J. Lara-Terán, Johanna Vargas-Rodríguez, Rubén Dueñas-Villamil, Vicente Bohórquez-Reyes, Carlos Martínez-Acosta, Esteban Gómez-Mesa, Julián Gaitán-Rozo, Julián Cortes-Colorado, Juliana Coral-Casas, Laura Horlandy-Gómez, Leonardo Bautista-Toloza, Leonardo Palacios, Lina Fajardo-Latorre, Luís Pino, Leonardo Rojas-Puentes, Patricia Rodríguez-Sánchez, Mauricio Herrera-Méndez, Mauricio Orozco‐Levi, Mónica Sosa-Briceño, Nelson L. Moreno, Oscar Sáenz-Morales, Pablo Amaya-González, Sergio A. Ramírez‐García, Víctor Hugo Nieto-Estrada, Virgil Carballo-Zárate, Virginia Abello-Polo,

Tópico(s)

Dermatological and COVID-19 studies

Resumo

Introduction: recent studies have reported the occurrence of thrombotic phenomena or coagulopathy in patients with COVID-19.There are divergent positions regarding the prevention, diagnosis, and treatment of these phenomena, and current clinical practice is based solely on deductions by extension from retrospective studies, case series, observational studies, and international guidelines developed prior to the pandemic.Objective: to generate a group of recommendations on the prevention, diagnosis and management of thrombotic complications associated with COVID-19.Methods: a rapid guidance was carried out applying the GRADE Evidence to Decision (EtD) frameworks and an iterative participation system, with statistical and qualitative analysis.Results: 31 clinical recommendations were generated focused on: a) Coagulation tests in symptomatic adults with suspected infection or confirmed SARS CoV-2 infection; b) Thromboprophylaxis in adults diagnosed with COVID-19 (Risk scales, thromboprophylaxis for outpatient, in-hospital management, and duration of thromboprophylaxis after discharge from hospitalization), c) Diagnosis and treatment of thrombotic complications, and d) Management of people with previous indication of anticoagulant agents.Conclusions: recommendations of this consensus guide clinical decision-making regarding the prevention, diagnosis, and treatment of thrombotic phenomena in patients with COVID-19, and represent an agreement that will help decrease the dispersion in clinical practices according to the challenge imposed by the pandemic.

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