Prognostic Significance of Combined Platelet Distribution Width and C-Reactive Protein Score in Esophageal Cancer
2020; International Institute of Anticancer Research (IIAR) Conferences 1997. Athens, Greece. Abstracts; Volume: 40; Issue: 10 Linguagem: Inglês
10.21873/anticanres.14586
ISSN1791-7530
AutoresYuta Kawakita, Satoru Motoyama, Yusuke Sato, Akiyuki Wakita, Yushi Nagaki, Kazuhiro Imai, Yoshihiro Minamiya,
Tópico(s)Venous Thromboembolism Diagnosis and Management
ResumoThe platelet distribution width (PDW) and serum C-reactive protein (CRP) levels are known to be predictive of prognosis in various malignancies. Our aim was to determine whether combining PDW and serum CRP levels produces a prognostic indicator for esophageal cancer (EC) patients.A total of 168 EC patients who underwent neoadjuvant therapy prior to esophagectomy were included in this study.We defined a combined PDW and CRP (CPC) score as follows: patients with both low pretherapeutic PDW (≤12.4 fl) and high postoperative serum CRP levels (≥0.5 mg/dl) were assigned a score of 2, while patients with one or neither of those were assigned a score of 1 or 0. A multivariable analysis showed that the CPC score was a significant risk factor for overall (p=0.006) and recurrence-free (p=0.004) survival.The CPC score is a strong prognostic indicator in EC patients.
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