Artigo Acesso aberto Revisado por pares

Eosinophils Protect Mice From Angiotensin-II Perfusion–Induced Abdominal Aortic Aneurysm

2020; Lippincott Williams & Wilkins; Volume: 128; Issue: 2 Linguagem: Inglês

10.1161/circresaha.120.318182

ISSN

1524-4571

Autores

Cong-Lin Liu, Xin Liu, Yuanyuan Zhang, Jing Liu, Chongzhe Yang, Songyuan Luo, Tianxiao Liu, Yunzhe Wang, Jes S. Lindholt, Axel Cosmus Pyndt Diederichsen, Lars Melholt Rasmussen, Marie Dahl, Galina K. Sukhova, Guanyi Lu, Gilbert R. Upchurch, Peter Libby, Junli Guo, Jinying Zhang, Guo‐Ping Shi,

Tópico(s)

Eosinophilic Disorders and Syndromes

Resumo

Blood eosinophil count and ECP (eosinophil cationic protein) associate with human cardiovascular diseases. Yet, whether eosinophils play a role in cardiovascular disease remains untested. The current study detected eosinophil accumulation in human and murine abdominal aortic aneurysm (AAA) lesions, suggesting eosinophil participation in this aortic disease.

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