Artigo Acesso aberto Revisado por pares

3D hydrogel mimics of the tumor microenvironment: the interplay among hyaluronic acid, stem cells and cancer cells

2020; Royal Society of Chemistry; Volume: 9; Issue: 1 Linguagem: Inglês

10.1039/d0bm00843e

ISSN

2047-4849

Autores

Sara Amorim, Diana Soares da Costa, Iva Pashkuleva, Celso A. Reis, Rui L. Reis, Ricardo A. Pires,

Tópico(s)

Liver physiology and pathology

Resumo

A 3D tumor microenvironment model is presented, combining hyaluronic acid (HA) and alginate. The model can be used to mimic the bioactivity of HA in gastric cancer, as well as the crosstalk between cancer cells and mesenchymal stem cells.

Referência(s)