3D hydrogel mimics of the tumor microenvironment: the interplay among hyaluronic acid, stem cells and cancer cells
2020; Royal Society of Chemistry; Volume: 9; Issue: 1 Linguagem: Inglês
10.1039/d0bm00843e
ISSN2047-4849
AutoresSara Amorim, Diana Soares da Costa, Iva Pashkuleva, Celso A. Reis, Rui L. Reis, Ricardo A. Pires,
Tópico(s)Liver physiology and pathology
ResumoA 3D tumor microenvironment model is presented, combining hyaluronic acid (HA) and alginate. The model can be used to mimic the bioactivity of HA in gastric cancer, as well as the crosstalk between cancer cells and mesenchymal stem cells.
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