Development of a CD8 co-receptor independent T-cell receptor specific for tumor-associated antigen MAGE-A4 for next generation T-cell-based immunotherapy
2021; BMJ; Volume: 9; Issue: 3 Linguagem: Inglês
10.1136/jitc-2020-002035
ISSN2051-1426
AutoresKathrin Davari, Tristan Holland, Laura Prassmayer, Giulia Longinotti, Kenneth Ganley, Lisa Pechilis, Iulia Diaconu, Prashant R. Nambiar, Michael S. Magee, Dolores J. Schendel, Daniel Sommermeyer, Christian Ellinger,
Tópico(s)T-cell and B-cell Immunology
ResumoThe cancer-testis antigen MAGE-A4 is an attractive target for T-cell-based immunotherapy, especially for indications with unmet clinical need like non-small cell lung or triple-negative breast cancer.
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