Produção Nacional
Revisado por pares
Larvicide Activity on Aedes aegypti of Essential Oil Nanoemulsion from the Protium heptaphyllum Resin
2020; Multidisciplinary Digital Publishing Institute; Volume: 25; Issue: 22 Linguagem: Inglês
10.3390/molecules25225333
ISSN1433-1373
AutoresCleidjane Gomes Faustino, Fernando Antônio de Medeiros, Allan Kardec Ribeiro Galardo, Alex Bruno Lobato Rodrigues, Rosany Lopes Martins, Yuri de Medeiros Souza Lima, Josean Fechine Tavares, Marcos Antônio Alves de Medeiros, Jáder Santos Cruz, Sheylla Susan Moreira da Silva de Almeida,
Tópico(s)Moringa oleifera research and applications
ResumoThe aim of this work was to prepare a nanoemulsion containing the essential oil of Protium heptaphyllum resin and to evaluate the larvicidal activity and the residual larvicidal effect against Aedes aegypti. The essential oil was identified by gas chromatography coupled to a mass spectrometer, and the nanoemulsions were prepared using a low-energy method and characterized by photon correlation spectroscopy. The results indicated the major constituents as p-cimene (27.70%) and α-Pinene (22.31%). Nanoemulsions had kinetic stability and a monomodal distribution in a hydrophilic-lipophilic balance of 14 with particle diameters of 115.56 ± 1.68 nn and zeta potential of −29.63 ± 3.46 mV. The nanoemulsion showed larvicidal action with LC50 = 2.91 µg∙mL−1 and residual larvicidal effect for 72 h after application to A. aegypti larvae. Consequently, the nanobiotechnological product derived from the essential oil of P. heptaphyllum resin could be used against infectious disease vectors.
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