Marine-derived fungi as a source of bioactive indole alkaloids with diversified structures
2020; Springer Science+Business Media; Volume: 3; Issue: 1 Linguagem: Inglês
10.1007/s42995-020-00072-w
ISSN2096-6490
AutoresZhi-Hui Meng, Tiantian Sun, Guo-Zheng Zhao, Yu-Fei Yue, Qing-Hua Chang, Hua‐Jie Zhu, Fei Cao,
Tópico(s)Alkaloids: synthesis and pharmacology
ResumoMarine-derived fungi are well known as rich sources of bioactive natural products. Growing evidences indicated that indole alkaloids, isolated from a variety of marine-derived fungi, have attracted considerable attention for their diverse, challenging structural complexity and promising bioactivities, and therefore, indole alkaloids have potential to be pharmaceutical lead compounds. Systemic compilation of the relevant literature. In this review, we demonstrated a comprehensive overview of 431 new indole alkaloids from 21 genera of marine-derived fungi with an emphasis on their structures and bioactivities, covering literatures published during 1982-2019.
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