Voltar
Revisão Acesso aberto Revisado por pares
BIBTEX RIS

Systematic Review of Sequencing Studies and Gene Expression Profiling in Familial Meniere Disease

2020; Multidisciplinary Digital Publishing Institute; Volume: 11; Issue: 12 Linguagem: Inglês

10.3390/genes11121414

ISSN

2073-4425

Autores

Alba Escalera‐Balsera, Pablo Román-Naranjo, José A. López‐Escámez,

Tópico(s)

Genetic Neurodegenerative Diseases

Resumo

Familial Meniere Disease (FMD) is a rare inner ear disorder characterized by episodic vertigo associated with sensorineural hearing loss, tinnitus and/or aural fullness. We conducted a systematic review to find sequencing studies segregating rare variants in FMD to obtain evidence to support candidate genes for MD. After evaluating the quality of the retrieved records, eight studies were selected to carry out a quantitative synthesis. These articles described 20 single nucleotide variants (SNVs) in 11 genes (

Referência(s)