Artigo Acesso aberto Revisado por pares

The Global and Local Distribution of RNA Structure throughout the SARS-CoV-2 Genome

2020; American Society for Microbiology; Volume: 95; Issue: 5 Linguagem: Inglês

10.1128/jvi.02190-20

ISSN

1098-5514

Autores

Rafael de Cesaris Araujo Tavares, Gandhar Mahadeshwar, Han Wan, Nicholas C. Huston, Anna Marie Pyle,

Tópico(s)

Animal Virus Infections Studies

Resumo

The RNA genome of SARS-CoV-2 is among the largest and most complex viral genomes, yet its RNA structural features remain relatively unexplored. Since RNA elements guide function in most RNA viruses, and they represent potential drug targets, it is essential to chart the architectural features of SARS-CoV-2 and pinpoint regions that merit focused study.

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