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BIBTEX RIS

The Role of Vitamin D in Small Animal Bone Metabolism

2020; Multidisciplinary Digital Publishing Institute; Volume: 10; Issue: 12 Linguagem: Inglês

10.3390/metabo10120496

2218-1989

Rafael Vessecchi Amorim Zafalon, Bruna Ruberti, Mariana Fragoso Rentas, Andressa Rodrigues Amaral, Thiago Henrique Annibale Vendramini, Fernanda Chicharo Chacar, Márcia Mery Kogika, Márcio Antônio Brunetto,

Parathyroid Disorders and Treatments

Dogs and cats have differences in vitamin D metabolism compared to other mammalian species, as they are unable to perform vitamin D cutaneous synthesis through sun exposure. Therefore, they are dependent on the dietary intake of this nutrient. The classic functions of vitamin D are to stimulate intestinal calcium and phosphate absorption, renal calcium and phosphate reabsorption and regulate bone mineral metabolism. Thus, it is an important nutrient for calcium and phosphorus homeostasis. This review highlights the evidence of the direct and indirect actions of vitamin D on bone mineral metabolism, the consequences of nutritional imbalances of this nutrient in small animals, as well as differences in vitamin D metabolism between different size dogs.