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Phenotypic Characterization of the Resistance Status of Anopheles gambiae s.l. from Oyem, North Gabon to Four Classes of Insecticides

2020; Volume: 7; Issue: 3 Linguagem: Inglês

10.17582/journal.jap/2020/7.3.20.25

2311-4096

Pyazzi Obame Ondo Kutomy, Aubin Armel Koumba, Silas Lendzele Sevidzem, Christophe Roland Zinga Koumba, Rodrigue Mintsa Nguéma, Boris Makanga, Audrey Prisca Mélodie Ovono, El Hadji Malick Ngom, Seynabou Diedhiou Mocote, Abdou Razack Safiou, Prospère Abessolo Mengue, Jacques François Mavoungou, Ousmane Faye,

Malaria Research and Control

This study attempts to characterise the resistance status of Anopheles gambiae s.l., a major vector of malaria to insecticides recommended by World Health Organization in Oyem, north Gabon.Indeed, larval collections were conducted in July 2020 (dry season) in 14 quarters of Oyem town.All anopheline larvae were collected from natural water reservoirs.They were bred to adult stage in the field laboratory.All the adults (n=560) identified belonged to the An.gambiae complex.Their susceptibility to insecticides (Deltamethrin 0.05%, Permethrin 0.75%, Lambdacyhalothrin 0.05%, Cyfluthrin 0.15%, DDT 4%, Bendiocarb 0.1% and Malathion 5%) was assessed using the WHO susceptibility test protocol.Susceptibility test results showed a weak knock-down effect response of Anopheles to these insecticides tested.These results indicates their resistance to 4% DDT and pyrethroids, with mortalities between 0% and 68%.However, these Anopheles shows some reasonable degree of sensitivity to Bendiocarb (mortality = 100%) and Malathion (mortality = 100%).The strong resistance of An. gambiae s.l. to Pyrethroids, the only family used in the impregnation of mosquito nets, indicates the need to design efficient malaria vector control strategies for Oyem.