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BIBTEX RIS

Water-soluble manganese porphyrins as good catalysts for cipro- and levofloxacin degradation: Solvent effect, degradation products and DFT insights

2020; Elsevier BV; Volume: 268; Linguagem: Inglês

10.1016/j.chemosphere.2020.129334

1879-1298

Ana Luísa Almeida Lage, Aline Capelão Marciano, Mateus F. Venâncio, Mirra Angelina Neres da Silva, Dayse Carvalho da Silva Martins,

Electrochemical Analysis and Applications

Synthetic manganese porphyrins (MnPs), in the presence of oxidants, were employed for the degradation of fluoroquinolone antibiotics. Ciprofloxacin (CIP) and levofloxacin (LEV) degradation by iodosylbenzene, iodobenzene diacetate, H2O2 and meta-chloroperbenzoic acid using water-soluble MnP catalysts yielded thirteen and nine products, respectively, seven of which have been proposed for the first time. The MnP catalysts have demonstrated the ability to degrade these antibiotics to a high degree (up to 100% degradation). The structures of the degradation products were proposed based on mass spectrometry analysis, and density functional theory calculations could confirm how the substituent moieties attached to the basic chemical structure of the fluoroquinolones influence the degradation reactions. CIP has been shown to be a more reactive substrate towards the porphyrinic catalysts tested because of its three-membered ring. However, the catalysts could almost completely degrade LEV, highlighting the ability of these porphyrins to act as catalysts to degrade environmental pollutants.