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Strain Imaging in Cardio-Oncology

2020; Elsevier BV; Volume: 2; Issue: 5 Linguagem: Inglês

10.1016/j.jaccao.2020.10.011

2666-0873

Jennifer E. Liu, Ana Barac, Paaladinesh Thavendiranathan, Marielle Scherrer‐Crosbie,

Polymer Nanocomposite Synthesis and Irradiation

Echocardiographic imaging is crucial for patient management during cardiotoxic cancer therapy. Left ventricular ejection fraction is the most commonly used parameter for identifying left ventricular dysfunction. However, it lacks sensitivity to detect subclinical changes in cardiac function due to cardiotoxic treatment. Global longitudinal strain (GLS) is the best studied strain parameter with established diagnostic and prognostic value. Multiple studies have demonstrated changes in GLS as an early marker of cardiotoxicity. This document serves as a primer to help clinicians in the acquisition and interpretation of strain in cardio-oncology. Cases with embedded videos illustrate a step-by-step approach to obtaining GLS measurements and common pitfalls to avoid. The document includes a concise summary of the indications of GLS in cardio-oncology and its role in guiding oncological therapy. Practical approaches on how to implement strain in the echo laboratory with guidance on training and quality assurance are also discussed.