
Cyclotides from Brazilian Palicourea sessilis and Their Effects on Human Lymphocytes
2021; American Chemical Society; Volume: 84; Issue: 1 Linguagem: Inglês
10.1021/acs.jnatprod.0c01069
ISSN1520-6025
AutoresMeri Emili F. Pinto, Lai Yue Chan, Johannes Koehbach, Seema Devi, Carsten Gründemann, Christian W. Gruber, Mário Gomes, Vanderlan da Silva Bolzani, Eduardo Maffud Cilli, David J. Craik,
Tópico(s)Toxin Mechanisms and Immunotoxins
ResumoCyclotides are plant-derived peptides found within five families of flowering plants (Violaceae, Rubiaceae, Fabaceae, Solanaceae, and Poaceae) that have a cyclic backbone and six conserved cysteine residues linked by disulfide bonds. Their presence within the Violaceae species seems ubiquitous, yet not all members of other families produce these macrocyclic peptides. The genus
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