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Sex differences in susceptibility, severity, and outcomes of coronavirus disease 2019: Cross-sectional analysis from a diverse US metropolitan area

2021; Public Library of Science; Volume: 16; Issue: 1 Linguagem: Inglês

10.1371/journal.pone.0245556

1932-6203

Farhaan Vahidy, Alan Pan, Hilda Ahnstedt, Yashasvee Munshi, H. Alex Choi, Yordanos M. Tiruneh, Khurram Nasir, Bita A. Kash, Julia Andrieni, Louise D. McCullough,

COVID-19 and Mental Health

Sex is increasingly recognized as an important factor in the epidemiology and outcome of many diseases. This also appears to hold for coronavirus disease 2019 (COVID-19). Evidence from China and Europe has suggested that mortality from COVID-19 infection is higher in men than women, but evidence from US populations is lacking. Utilizing data from a large healthcare provider, we determined if males, as compared to females have a higher likelihood of SARS-CoV-2 susceptibility, and if among the hospitalized COVID-19 patients, male sex is independently associated with COVID-19 severity and poor in-hospital outcomes.