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Cross-Reactive Anti-Nucleocapsid Protein Immunity against Crimean-Congo Hemorrhagic Fever Virus and Hazara Virus in Multiple Species

2021; American Society for Microbiology; Volume: 95; Issue: 7 Linguagem: Inglês

10.1128/jvi.02156-20

1098-5514

Merve Kalkan-Yazıcı, Elif Karaaslan, Nesibe Selma Çetin, Sevde Hasanoğlu, Filiz Güney, Ümit Zeybek, Mehmet Ziya Doymaz,

Vector-Borne Animal Diseases

Crimean-Congo hemorrhagic fever virus (CCHFV) and Hazara virus (HAZV), members of the Nairoviridae family, are transmitted to mammals by tick bites. CCHFV is considered a severe threat to public health and causes hemorrhagic diseases with a high mortality rate, and there are neither preventative nor therapeutic medications against CCHFV disease.