Artigo Acesso aberto Produção Nacional Revisado por pares

The importance of intramolecular hydrogen bonds on the translocation of the small drug piracetam through a lipid bilayer

2021; Royal Society of Chemistry; Volume: 11; Issue: 2 Linguagem: Inglês

10.1039/d0ra09995c

ISSN

2046-2069

Autores

João T. S. Coimbra, Ralph Feghali, Rui P. Ribeiro, Maria J. Ramos, Pedro Alexandrino Fernandes,

Tópico(s)

Neuroscience and Neuropharmacology Research

Resumo

Using computational strategies and an analogue compound, we explore and measure the impact of intramolecular hydrogen bonds on the translocation of the small drug piracetam, through biological membrane models.

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