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Photoprotective potential of a Tunisian halophyte plant Carpobrotus edulis L

2021; Elsevier BV; Volume: 42; Linguagem: Inglês

10.1016/j.eujim.2021.101286

1876-3839

Mohamed Ali Lassoued, Nour El Houda Ben Fatma, Mariem Haj Romdhane, Adel Faidi, Hatem Majdoub, Souad Sfar,

Essential Oils and Antimicrobial Activity

Different strategies are applicable to protect skin against the harmful effects which may appear due to an overexposure to UV radiation including the use of sunscreens. Natural polyphenols have shown an interesting activity as photoprotectors. This study aimed to assess the potentiality of a Tunisian halophyte plant, Carpobrotus edulis L. (CE) as a candidate for topical photoprotection. A phytochemical characterization of CE aqueous leaf extract was processed by quantification of total polyphenols and flavonoids contents as well as by FT-IR, UV and LC-MS analysis. The plant extract was, then, incorporated into an oil-in-water (O/W) cream and assessed for its in vitro antioxidant properties and sun protection factor (SPF). Phytochemical characterization highlighted the richness of the aqueous extract in polyphenols. LC-MS analysis permitted the identification of 20 phenolic compounds. Catechin, procyanidin B2, dihydromyricetin and syringetin-3-O-rutinoside were the most predominant components (19.39%, 16.04%, 12.85% and 14.28% respectively). UV spectrophotometric analyses showed that CE extract absorbed in the UV region (190–400 nm). C.E crude extract exhibited, at the concentration of 1000 µg/ml, a high photoprotective effect with a SPF value of 6.996 ± 0.174 corresponding to a percent of UV blockage ranging from 80 to 90%. Besides, when it was incorporated into an O/W emulsion at a concentration of 10% (m/m), it presented a good antioxidant activity (DPPH inhibition (%) ≈ 70%) and an in vitro SPF value of 1.626 ± 0.466 corresponding to a percent of UV blockage ≈50%. These results suggest that Carpobrotus edulis L. could be a good topical photoprotective agent.