Portal de Periódicos da CAPES

Laparoscopic versus open resection of intrahepatic cholangiocarcinoma: nationwide analysis

2021; Oxford University Press; Volume: 108; Issue: 4 Linguagem: Inglês

10.1093/bjs/znaa110

1365-2168

Christian Hobeika, François Cauchy, David Fuks, Louise Barbier, Jean‐Michel Fabre, Emmanuel Boleslawski, J.-M. Régimbeau, Olivier Farges, F.R. Pruvot, Patrick Pessaux, Ephrem Salamé, Olivier Soubrane, Éric Vibert, Olivier Scatton, Claire Goumard, Brice Gayet, Daniel Cherqui, Takeo Nomi, Nassima Oudafal, Takayuki Kawai, Shohei Komatsu, Shinya Okumura, Niccolò Petrucciani, Alexis Laurent, Petru Bucur, B. Tréchot, Julio Núñez, Michele Tedeschi, M.-A. Allard, Nicolas Golse, Oriana Ciacio, Gabriella Pittau, António Sá Cunha, R. Adam, Christophe Laurent, L. Chiche, P. Léourier, Lionel Rebibo, Laura Ferrè, Régis Souche, Jean Chauvat, François Jehaes, Kayvan Mohkam, Mickaël Lesurtel, Christian Ducerf, Jean‐Yves Mabrut, T. Hor, François Paye, Pierre Balladur, Bertrand Suc, Fabrice Muscari, Guillaume Y. Millet, Mehdi El Amrani, Christine K. Ratajczak, Katia Lécolle, Stéphanie Truant, Ali-Reza Kianmanesh, Tatiana Codjia, Lilian Schwarz, Édouard Girard, J. Abba, Christian Létoublon, Mircea Chirica, Abenavoli Carmelo, Charles Vanbrugghe, Zineb Cherkaoui, Xavier Unterteiner, Riccardo Memeo, Emmanuel Buc, Émilie Lermite, J. Barbieux, M. Bougard, Ugo Marchèse, Jacques Ewald, Olivier Turini, Alexandre Thobie, Benjamin Menahem, A. Mulliri, Jean Lubrano, J. Zemour, H. Fagot, Guillaume Passot, Émilie Grégoire, Jean Hardwigsen, Y.P. Le Treut, D Patrice,

Pancreatic and Hepatic Oncology Research

The relevance of laparoscopic resection of intrahepatic cholangiocarcinoma (ICC) remains debated. The aim of this study was to compare laparoscopic (LLR) and open (OLR) liver resection for ICC, with specific focus on textbook outcome and lymph node dissection (LND).Patients undergoing LLR or OLR for ICC were included from two French, nationwide hepatopancreatobiliary surveys undertaken between 2000 and 2017. Patients with negative margins, and without transfusion, severe complications, prolonged hospital stay, readmission or death were considered to have a textbook outcome. Patients who achieved both a textbook outcome and LND were deemed to have an adjusted textbook outcome. OLR and LLR were compared after propensity score matching.In total, 548 patients with ICC (127 LLR, 421 OLR) were included. Textbook-outcome and LND completion rates were 22.1 and 48.2 per cent respectively. LLR was independently associated with a decreased rate of LND (odds ratio 0.37, 95 per cent c.i. 0.20 to 0.69). After matching, 109 patients remained in each group. LLR was associated with a decreased rate of transfusion (7.3 versus 21.1 per cent; P = 0.001) and shorter hospital stay (median 7 versus 14 days; P = 0.001), but lower rate of LND (33.9 versus 73.4 per cent; P = 0.001). Patients who underwent LLR had lower rate of adjusted TO completion than patients who had OLR (6.5 versus 17.4 per cent; P = 0.012).The laparoscopic approach did not substantially improve quality of care of patients with resectable ICC.