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Artigo Acesso aberto Revisado por pares
BIBTEX RIS

Protein arginine methyltransferase 1 contributes to the development of allergic rhinitis by promoting the production of epithelial-derived cytokines

2021; Elsevier BV; Volume: 147; Issue: 5 Linguagem: Inglês

10.1016/j.jaci.2020.12.646

ISSN

1097-6825

Autores

Jiyeon Park, Joo Hee Choi, Sang‐Nam Lee, Hyung‐Ju Cho, Ji-Suk Ahn, Yong-Bum Kim, Do-Yong Park, Sang Chul Park, Soo In Kim, Min‐Jung Kang, Ah-Ra Jang, Jae-Hun Ahn, Tae-Sung Lee, Dong‐Yeon Kim, Sung Jae Shin, Joo‐Heon Yoon, Jong‐Hwan Park,

Tópico(s)

Epigenetics and DNA Methylation

Resumo

Arginine methylation is a posttranslational modification mediated by protein arginine methyltransferases (PRMTs). Although previous studies have shown that PRMT1 contributes to the severity of allergic airway inflammation or asthma, the underlying mechanism is poorly understood.

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