Produção Nacional
Revisado por pares
Peripheral muscle strength is associated with aerobic fitness and use of antibiotics in patients with cystic fibrosis
2021; Wiley; Volume: 75; Issue: 5 Linguagem: Inglês
10.1111/ijcp.14050
ISSN1742-1241
AutoresFernanda Maria Vendrusculo, Gabriela Sabino Bueno, Mailise Fátima Gheller, Natália Evangelista Campos, Daniele Schiwe, Ingrid Almeida, Nicolas Becker, João Paulo Heinzmann‐Filho, Márcio Vinı́cius Fagundes Donadio,
Tópico(s)Asthma and respiratory diseases
ResumoInternational Journal of Clinical PracticeVolume 75, Issue 5 e14050 ORIGINAL PAPER Peripheral muscle strength is associated with aerobic fitness and use of antibiotics in patients with cystic fibrosis Fernanda Maria Vendrusculo, Fernanda Maria Vendrusculo Laboratory of Pediatric Physical Activity, Centro Infant, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Rio Grande do Sul, BrazilSearch for more papers by this authorGabriela Sabino Bueno, Gabriela Sabino Bueno Laboratory of Pediatric Physical Activity, Centro Infant, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Rio Grande do Sul, BrazilSearch for more papers by this authorMailise Fátima Gheller, Mailise Fátima Gheller Laboratory of Pediatric Physical Activity, Centro Infant, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Rio Grande do Sul, BrazilSearch for more papers by this authorNatália Evangelista Campos, Natália Evangelista Campos Laboratory of Pediatric Physical Activity, Centro Infant, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Rio Grande do Sul, BrazilSearch for more papers by this authorDaniele Schiwe, Daniele Schiwe Laboratory of Pediatric Physical Activity, Centro Infant, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Rio Grande do Sul, BrazilSearch for more papers by this authorIngrid Silveira de Almeida, Ingrid Silveira de Almeida Laboratory of Pediatric Physical Activity, Centro Infant, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Rio Grande do Sul, BrazilSearch for more papers by this authorNicolas Acosta Becker, Nicolas Acosta Becker Laboratory of Pediatric Physical Activity, Centro Infant, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Rio Grande do Sul, BrazilSearch for more papers by this authorJoão Paulo Heinzmann-Filho, João Paulo Heinzmann-Filho Laboratory of Pediatric Physical Activity, Centro Infant, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Rio Grande do Sul, BrazilSearch for more papers by this authorMárcio Vinícius Fagundes Donadio, Corresponding Author Márcio Vinícius Fagundes Donadio mdonadio@pucrs.br orcid.org/0000-0001-8836-9109 Laboratory of Pediatric Physical Activity, Centro Infant, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Rio Grande do Sul, Brazil Correspondence Márcio Vinícius Fagundes Donadio, Laboratory of Pediatric Physical Activity, Centro Infant, Av. Ipiranga, 6690, 2° andar, Porto Alegre, Rio Grande do Sul, CEP 90610-000, Brazil. Email: mdonadio@pucrs.brSearch for more papers by this author Fernanda Maria Vendrusculo, Fernanda Maria Vendrusculo Laboratory of Pediatric Physical Activity, Centro Infant, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Rio Grande do Sul, BrazilSearch for more papers by this authorGabriela Sabino Bueno, Gabriela Sabino Bueno Laboratory of Pediatric Physical Activity, Centro Infant, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Rio Grande do Sul, BrazilSearch for more papers by this authorMailise Fátima Gheller, Mailise Fátima Gheller Laboratory of Pediatric Physical Activity, Centro Infant, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Rio Grande do Sul, BrazilSearch for more papers by this authorNatália Evangelista Campos, Natália Evangelista Campos Laboratory of Pediatric Physical Activity, Centro Infant, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Rio Grande do Sul, BrazilSearch for more papers by this authorDaniele Schiwe, Daniele Schiwe Laboratory of Pediatric Physical Activity, Centro Infant, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Rio Grande do Sul, BrazilSearch for more papers by this authorIngrid Silveira de Almeida, Ingrid Silveira de Almeida Laboratory of Pediatric Physical Activity, Centro Infant, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Rio Grande do Sul, BrazilSearch for more papers by this authorNicolas Acosta Becker, Nicolas Acosta Becker Laboratory of Pediatric Physical Activity, Centro Infant, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Rio Grande do Sul, BrazilSearch for more papers by this authorJoão Paulo Heinzmann-Filho, João Paulo Heinzmann-Filho Laboratory of Pediatric Physical Activity, Centro Infant, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Rio Grande do Sul, BrazilSearch for more papers by this authorMárcio Vinícius Fagundes Donadio, Corresponding Author Márcio Vinícius Fagundes Donadio mdonadio@pucrs.br orcid.org/0000-0001-8836-9109 Laboratory of Pediatric Physical Activity, Centro Infant, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Rio Grande do Sul, Brazil Correspondence Márcio Vinícius Fagundes Donadio, Laboratory of Pediatric Physical Activity, Centro Infant, Av. Ipiranga, 6690, 2° andar, Porto Alegre, Rio Grande do Sul, CEP 90610-000, Brazil. Email: mdonadio@pucrs.brSearch for more papers by this author First published: 26 January 2021 https://doi.org/10.1111/ijcp.14050Citations: 3 Fernanda Maria Vendrusculo and Gabriela Sabino Bueno contributed equally to the manuscript. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Abstract Aims Individuals with cystic fibrosis (CF) may develop muscle abnormalities, although little is known on its clinical and functional impact. This study aimed to evaluate the association of peripheral muscle strength with aerobic fitness, habitual physical activity, lung function and the use of antibiotics (ATB) in patients with CF. Methods A cross-sectional study where individuals aged ≥6 years underwent peripheral muscle strength evaluation (biceps, quadriceps and hamstrings) and performed a cardiopulmonary exercise test. Demographic, anthropometric, genetic, lung function and total days of ATB use within 1 year of tests were also collected. Results Correlation was found for biceps (r = .45; P = .002) strength with the peak oxygen consumption (VO2peak). Muscle strength (biceps and quadriceps) also correlated with the ventilatory equivalent for oxygen consumption (VE/VO2) at anaerobic threshold (AT) and with the ventilatory equivalent for carbon dioxide production (VE/VCO2) both at AT and peak exercise. Negative correlations were found for quadriceps (r = −.39) and hamstrings (r = −.42) with the total days of ATB use in the following year. Patients needing to use ATB presented lower biceps strength (P = .05) and individuals with VO2peak lower than 37 mL·kg−1·min−1 presented lower muscle strength for both biceps (P = .01) and quadriceps (P = .02). Conclusions The results have shown that peripheral muscle strength is associated with aerobic fitness and the use of antibiotics in patients with CF. DISCLOSURES The authors have no conflict of interests to declare. Citing Literature Supporting Information Filename Description ijcp14050-sup-0001-FigS1.tifTIFF image, 65.3 KB Fig S1 Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. Volume75, Issue5May 2021e14050 RelatedInformation
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