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Does Big Mean Evil? Giant, but Benign Uterine Leiomyoma: Case Report and Review of the Literature

2021; Thieme Medical Publishers (Germany); Volume: 43; Issue: 01 Linguagem: Inglês

10.1055/s-0040-1721351

1806-9339

Luiz Gustavo Oliveira Brito, Natalia Lysei Ueno, Maira Rossmann Machado,

Gynecological conditions and treatments

Abstract Uterine leiomyoma is the most prevalent benign type of gynecological tumor. It affects more than 80% of women worldwide and, within this group, more than 50% may be asymptomatic. However, large fibroid volumes may be associated with symptoms of extrinsic compression, and most of the cases do not present atypical cells. We present the case of a 49-year-old woman who underwent a total abdominal hysterectomy of a 13.5-kg uterine leiomyoma with no malignancies at histopathology and review the literature about giant uterine leiomyomas and their clinical repercussion. We concluded that large volumes do not always pose a threat regarding malignancy; however, future molecular studies are needed to investigate giant uterine fibroids.