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Múltiples úlceras perianales en relación con el uso de una pomada antihemorroidal con acetónido de triamcinolona, lidocaína y pentosano polisulfato sódico como principios activos: una serie de 11 pacientes españoles

2021; Elsevier BV; Volume: 112; Issue: 7 Linguagem: Inglês

10.1016/j.ad.2021.02.002

1695-4734

Dídac Marín-Piñero, Maribel Iglesias‐Sancho, Jaime Company‐Quiroga, C. Martínez‐Morán, Patricia Pérez Feal, I. Vázquez‐Osorio, Pedro Rodríguez‐Jiménez, J. Sánchez-Estella, Ana Suárez‐Valle, L Buzón, E. Martín-Sáez, Sara García‐Rodiño, A. Sáez-Vicente, D.M. Arranz-Sánchez, I. Cervigón-González, Enrique del Río,

Colorectal and Anal Carcinomas

The development of perianal ulcers related to the use of a hemorrhoidal ointment has not been reported in the literature. We describe a series of 11 patients who were treated for perianal ulcers in 10 Spanish hospitals after they used the same ointment containing the active ingredients triamcinolone acetonide, lidocaine, and pentosan polysulfate sodium. No prior or concomitant conditions suggesting an alternative cause for the condition could be identified, and after the patients stopped using the ointment, their ulcers cleared completely in 8 weeks on average. This case series shows the damage that can be caused by an over-the-counter pharmaceutical product used without medical follow-up. It also illustrates the need to ask patients with perianal ulcers about any topical agents used before the lesions appeared.