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COVID-19 in a temporal relation to the onset of multiple sclerosis

2021; Elsevier BV; Volume: 50; Linguagem: Inglês

10.1016/j.msard.2021.102863

2211-0356

Yára Dadalti Fragoso, Filippe A.S. Pacheco, Guilherme Lopes da Silveira, Rodrigo Azevedo de Oliveira, Vitor Martinez de Carvalho, Ana Luiza Cabrera Martimbianco,

Olfactory and Sensory Function Studies

Neurological complications of COVID-19 have been described. We present the case of a 27-year-old woman who developed COVID-19 in April 2020. She continued to present anosmia and ageusia eight months later. Six months after contracting COVID-19, she developed dysesthesia, hypoesthesia and hyperreflexia. Her magnetic resonance imaging showed demyelinating lesions, of which two were enhanced by gadolinium. She was positive for oligoclonal bands in her spinal fluid. This patient developed multiple sclerosis with a temporal relationship to COVID-19. We believe that SARS-CoV-2 led to her autoimmune disease through a virus-induced neuroimmunopathological condition.