Produção Nacional
Revisado por pares
Effectiveness of the piperine-supplemented Curcuma longa L. in metabolic control of patients with type 2 diabetes: a randomised double-blind placebo-controlled clinical trial
2021; Taylor & Francis; Volume: 72; Issue: 7 Linguagem: Inglês
10.1080/09637486.2021.1885015
ISSN1465-3478
AutoresJoana Furtado de Figueiredo Neta, Vívian Saraiva Veras, Danilo Ferreira de Sousa, Maria da Conceição dos Santos Oliveira Cunha, Maria Veraci Oliveira Queiroz, José Cláudio Garcia Lira Neto, Marta María Coelho Damasceno, Márcio Flávio Moura de Araújo, Roberto Wagner Júnior Freire de Freitas,
Tópico(s)Medicinal Plants and Neuroprotection
ResumoThere is robust evidence of using Curcuma longa L. in reducing metabolic levels in people with diabetes. This study analysed the effectiveness of Curcuma longa L. in the metabolic control of patients with type 2 diabetes in Brazil. A randomised double-blind placebo-controlled clinical trial was conducted with 71 participants divided into a Curcuma longa L. group (500 mg/day with piperine 5 mg) and a placebo group, for 120 days. Anthropometric, clinical and biochemical variables were evaluated at baseline, 60 and 120 days after the beginning of the intervention. Paired and independent Student's t-test and chi-square test were used for statistical analysis. The curcuma group presented a significantly decreased glycaemia (p=.013), glycated haemoglobin (p=.015), HOMA index (p=.037) and triglycerides (TGs) (p=.002). The use of piperine-added Curcuma longa L. was effective in the glycaemic and TG control of patients with type 2 diabetes.
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