Artigo Acesso aberto Revisado por pares

Bacteriophage Treatment Rescues Mice Infected with Multidrug-Resistant Klebsiella pneumoniae ST258

2021; American Society for Microbiology; Volume: 12; Issue: 1 Linguagem: Inglês

10.1128/mbio.00034-21

ISSN

2161-2129

Autores

Shayla Hesse, Natalia Małachowa, Adeline R. Porter, Brett A. Freedman, Scott D. Kobayashi, Donald J. Gardner, Dana Scott, Sankar Adhya, Frank R. DeLeo,

Tópico(s)

Viral gastroenteritis research and epidemiology

Resumo

Infections caused by multidrug-resistant K. pneumoniae pose a serious threat to at-risk patients and present a therapeutic challenge for clinicians. Bacteriophage (phage) therapy is an alternative treatment approach that has been associated with positive clinical outcomes when administered experimentally to patients with refractory bacterial infections.

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