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Immune status, well-being and gut microbiota in military supplemented with synbiotic ice cream and submitted to field training: a randomised clinical trial

2021; Cambridge University Press; Volume: 126; Issue: 12 Linguagem: Inglês

10.1017/s0007114521000568

1475-2662

Maria Carolina Pelatieri Valle, Isabel A. Vieira, Luciana Carvalho Fino, Darlila Aparecida Gallina, Andrea Maculano Esteves, Diogo Thimóteo da Cunha, Lucélia Cabral, Fabiana Braga Benatti, Mário Roberto Maróstica, Ângela Giovana Batista, Rosângela dos Santos, Gláucia María Pastore, Adilson Sartoratto, Kátia Sivieri, Polyana Tizioto, Luiz Lehmann Coutinho, Adriane Elisabete Costa Antunes,

Gut microbiota and health

Abstract Strenuous physical activity, sleep deprivation and psychological stress are common features of military field training. The present study aimed to evaluate the effects of supplementation with a synbiotic ice cream on salivary IgA, gastrointestinal symptoms, well-being indicators and gut microbiota in young military participants undergoing field training. Sixty-five military completed the study: one group was supplemented for 30 d with synbiotic ice cream containing: 2·1 × 10 8 CFU/g for Lactobacillus acidophilus LA-5 and 2·7 × 10 9 CFU/g for Bifidobacterium animalis BB-12 and 2·3 g of inulin in the 60 g of ice cream at manufacture, and the other with a placebo ice cream. Volunteers were evaluated at pre-supplementation (baseline), post-supplementation and after a 5-d military training. Bifidobacterium and Lactobacillus genera were measured in stool samples and both showed a higher differential abundance post-supplementation and training. Salivary IgA and gastrointestinal symptoms decreased at post-training in both groups ( P < 0·05; main effect of time); however, supplementation with synbiotic did not mitigate this effect. Tenseness and sleepiness were decreased in the synbiotic-treated group, but not in the placebo group at post-military training ( P = 0·01 and 0·009, respectively; group × time effect). The other well-being indicators were not affected by the synbiotic supplementation. In conclusion, 30 d of synbiotic ice cream supplementation containing inulin, L. acidophilus LA-5 and B. animalis BB-12 favourably modulated gut microbiota and improved tenseness and sleepiness in healthy young military undergoing a 5-d field training. These improvements may be relevant to this population as they may influence the decision-making process in an environment of high physical and psychological stress.