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The great escape? SARS-CoV-2 variants evading neutralizing responses

2021; Cell Press; Volume: 29; Issue: 3 Linguagem: Inglês

10.1016/j.chom.2021.02.010

1934-6069

Jérémie Prévost, Andrés Finzi,

COVID-19 epidemiological studies

In the latest issues of Cell Host & Microbe and Cell, three articles describe new mutations in the SARS-CoV-2 Spike receptor binding domain that escape neutralizing responses. These highlight the importance of surveillance of SARS-CoV-2 evolution to anticipate and manage new variants that could impact reinfection, vaccine efficacy, and immunotherapies.