Artigo Acesso aberto Revisado por pares

A venous-specific purinergic signaling cascade initiated by Pannexin 1 regulates TNFα-induced increases in endothelial permeability

2021; American Association for the Advancement of Science; Volume: 14; Issue: 672 Linguagem: Inglês

10.1126/scisignal.aba2940

ISSN

1937-9145

Autores

Daniela Begandt, H. Skye Comstra, Samuel A. Molina, Nenja Krüger, Claire A. Ruddiman, Yen‐Lin Chen, Xiaobin Chen, Lauren A. Biwer, Scott R. Johnstone, Alexander W. Lohman, Miranda E. Good, Leon J. DeLalio, Kwangseok Hong, Hannah Bacon, Zhen Yan, Swapnil K. Sonkusare, Michael Koval, Brant E. Isakson,

Tópico(s)

Heme Oxygenase-1 and Carbon Monoxide

Resumo

A pathway underlying the TNFα-induced decrease in endothelial barrier function is found in veins but not arteries.

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