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Oxidative Stress and Endoplasmic Reticulum Stress in Rare Respiratory Diseases

2021; Multidisciplinary Digital Publishing Institute; Volume: 10; Issue: 6 Linguagem: Inglês

10.3390/jcm10061268

2077-0383

María Magallón, Sara Pastor, Ana Carrión, Lucía Bañuls, Daniel Pellicer, Silvia Castillo, Sergio Bondía, María Mercedes Navarro‐García, Cruz González, Francisco Dası́,

Sulfur Compounds in Biology

Several studies have shown that some rare respiratory diseases, such as alpha-1 antitrypsin deficiency (AATD), idiopathic pulmonary fibrosis (IPF), cystic fibrosis (CF), and primary ciliary dyskinesia (PCD) present oxidative stress (OS) and endoplasmic reticulum (ER) stress. Their involvement in these pathologies and the use of antioxidants as therapeutic agents to minimize the effects of OS are discussed in this review.