SARS‐CoV‐2‐specific IgG1/IgG3 but not IgM in children with Pediatric Inflammatory Multi‐System Syndrome
2021; Wiley; Volume: 32; Issue: 5 Linguagem: Inglês
10.1111/pai.13504
ISSN1399-3038
AutoresMarisol Pérez-Toledo, Sian Faustini, Siân E. Jossi, Adrian M. Shields, Edith Marcial‐Juárez, Hari Krishnan Kanthimathinathan, Joel D. Allen, Yasunori Watanabe, Margaret Goodall, Benjamin E. Willcox, Carrie R. Willcox, Mahboob Salim, David C. Wraith, Tonny Veenith, Eleni Syrimi, Mark T. Drayson, Deepthi Jyothish, Eslam Al‐Abadi, Ashish Chikermane, Steven B. Welch, Kavitha Masilamani, Scott Hackett, Max Crispin, Barnaby R. Scholefield, Adam F. Cunningham, Alex Richter,
Tópico(s)Respiratory viral infections research
ResumoPediatric Allergy and ImmunologyVolume 32, Issue 5 p. 1125-1129 LETTER TO THE EDITOR SARS-CoV-2-specific IgG1/IgG3 but not IgM in children with Pediatric Inflammatory Multi-System Syndrome Marisol Perez-Toledo, Marisol Perez-Toledo orcid.org/0000-0002-5734-255X Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK Contribution: Conceptualization (equal), Data curation (equal), Formal analysis (equal), Investigation (equal), Writing - review & editing (equal)Search for more papers by this authorSian E. Faustini, Sian E. Faustini Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK Contribution: Conceptualization (equal), Data curation (equal), Formal analysis (equal), Investigation (equal), Writing - review & editing (equal)Search for more papers by this authorSian E. Jossi, Sian E. Jossi Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK Contribution: Conceptualization (equal), Data curation (equal), Formal analysis (equal), Investigation (equal), Writing - review & editing (equal)Search for more papers by this authorAdrian M. Shields, Adrian M. Shields Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK Contribution: Data curation (supporting), Writing - review & editing (supporting)Search for more papers by this authorEdith Marcial-Juarez, Edith Marcial-Juarez Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK Contribution: Investigation (equal), Writing - review & editing (supporting)Search for more papers by this authorHari Krishnan Kanthimathinathan, Hari Krishnan Kanthimathinathan Birmingham Clinical Trials Unit, University of Birmingham, Birmingham, UK Paediatric Intensive Care Unit, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK Contribution: Resources (supporting), Writing - review & editing (supporting)Search for more papers by this authorJoel D. Allen, Joel D. Allen School of Biological Sciences, University of Southampton, Southampton, UK Contribution: Resources (supporting), Writing - review & editing (supporting)Search for more papers by this authorYasunori Watanabe, Yasunori Watanabe Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, Oxford, UK Contribution: Resources (supporting), Writing - review & editing (supporting)Search for more papers by this authorMargaret Goodall, Margaret Goodall Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK Contribution: Investigation (supporting), Resources (equal)Search for more papers by this authorBenjamin E. Willcox, Benjamin E. Willcox Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK Contribution: Resources (lead), Writing - review & editing (supporting)Search for more papers by this authorCarrie R. Willcox, Carrie R. Willcox Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK Contribution: Resources (lead), Writing - review & editing (supporting)Search for more papers by this authorMahboob Salim, Mahboob Salim Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK Contribution: Resources (lead), Writing - review & editing (supporting)Search for more papers by this authorDavid C. Wraith, David C. Wraith Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK Contribution: Formal analysis (supporting), Writing - review & editing (supporting)Search for more papers by this authorTonny V. Veenith, Tonny V. Veenith Department of Critical Care Medicine, University Hospitals Birmingham NHS Trust, Birmingham, UK Contribution: Resources (supporting), Writing - review & editing (supporting)Search for more papers by this authorEleni Syrimi, Eleni Syrimi Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK Contribution: Data curation (supporting), Resources (supporting)Search for more papers by this authorMark T. Drayson, Mark T. Drayson Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK Contribution: Data curation (supporting), Formal analysis (supporting), Writing - review & editing (supporting)Search for more papers by this authorDeepthi Jyothish, Deepthi Jyothish Department of General Paediatrics, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK Contribution: Resources (supporting), Writing - review & editing (supporting)Search for more papers by this authorEslam Al-Abadi, Eslam Al-Abadi Birmingham Clinical Trials Unit, University of Birmingham, Birmingham, UK Childhood Arthritis and Rheumatic Diseases Unit, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK Contribution: Resources (supporting), Writing - review & editing (supporting)Search for more papers by this authorAshish Chikermane, Ashish Chikermane Department of Cardiology, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK Contribution: Resources (supporting), Writing - review & editing (supporting)Search for more papers by this authorSteven B. Welch, Steven B. Welch Department of Paediatrics, Birmingham Chest Clinic and Heartlands Hospital, University Hospitals Birmingham, Birmingham, UK Contribution: Resources (supporting), Writing - review & editing (supporting)Search for more papers by this authorKavitha Masilamani, Kavitha Masilamani Department of General Paediatrics, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK Contribution: Resources (supporting), Writing - review & editing (supporting)Search for more papers by this authorScott Hackett, Scott Hackett West Midlands Immunodeficiency Centre, Heartlands Hospital, University Hospitals Birmingham, Birmingham, UK Contribution: Resources (supporting), Writing - review & editing (supporting)Search for more papers by this authorMax Crispin, Max Crispin School of Biological Sciences, University of Southampton, Southampton, UK Contribution: Resources (lead), Writing - review & editing (equal)Search for more papers by this authorBarnaby R. Scholefield, Corresponding Author Barnaby R. Scholefield [email protected] Paediatric Intensive Care Unit, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK Correspondence Alex G. Richter, Adam F. Cunningham, Institute of Immunology and Immunotherapy, University of Birmingham, B15 2TT Birmingham, UK. Emails: [email protected] (AGR); [email protected] (AFC) Barnaby R. Scholefield, Paediatric Intensive Care Unit, Birmingham Women's and Children's NHS Foundation Trust, B4 6NH Birmingham, UK. Email: [email protected] Contribution: Conceptualization (equal), Data curation (equal), Formal analysis (equal), Resources (equal), Writing - original draft (equal), Writing - review & editing (equal)Search for more papers by this authorAdam F. Cunningham, Corresponding Author Adam F. Cunningham [email protected] Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK Correspondence Alex G. Richter, Adam F. Cunningham, Institute of Immunology and Immunotherapy, University of Birmingham, B15 2TT Birmingham, UK. Emails: [email protected] (AGR); [email protected] (AFC) Barnaby R. Scholefield, Paediatric Intensive Care Unit, Birmingham Women's and Children's NHS Foundation Trust, B4 6NH Birmingham, UK. Email: [email protected] Contribution: Conceptualization (equal), Formal analysis (equal), Supervision (equal), Writing - original draft (equal), Writing - review & editing (equal)Search for more papers by this authorAlex G. Richter, Corresponding Author Alex G. Richter [email protected] Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK Correspondence Alex G. Richter, Adam F. Cunningham, Institute of Immunology and Immunotherapy, University of Birmingham, B15 2TT Birmingham, UK. Emails: [email protected] (AGR); [email protected] (AFC) Barnaby R. Scholefield, Paediatric Intensive Care Unit, Birmingham Women's and Children's NHS Foundation Trust, B4 6NH Birmingham, UK. Email: [email protected] Contribution: Conceptualization (equal), Supervision (equal), Writing - original draft (equal), Writing - review & editing (equal)Search for more papers by this author Marisol Perez-Toledo, Marisol Perez-Toledo orcid.org/0000-0002-5734-255X Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK Contribution: Conceptualization (equal), Data curation (equal), Formal analysis (equal), Investigation (equal), Writing - review & editing (equal)Search for more papers by this authorSian E. Faustini, Sian E. Faustini Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK Contribution: Conceptualization (equal), Data curation (equal), Formal analysis (equal), Investigation (equal), Writing - review & editing (equal)Search for more papers by this authorSian E. Jossi, Sian E. Jossi Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK Contribution: Conceptualization (equal), Data curation (equal), Formal analysis (equal), Investigation (equal), Writing - review & editing (equal)Search for more papers by this authorAdrian M. Shields, Adrian M. Shields Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK Contribution: Data curation (supporting), Writing - review & editing (supporting)Search for more papers by this authorEdith Marcial-Juarez, Edith Marcial-Juarez Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK Contribution: Investigation (equal), Writing - review & editing (supporting)Search for more papers by this authorHari Krishnan Kanthimathinathan, Hari Krishnan Kanthimathinathan Birmingham Clinical Trials Unit, University of Birmingham, Birmingham, UK Paediatric Intensive Care Unit, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK Contribution: Resources (supporting), Writing - review & editing (supporting)Search for more papers by this authorJoel D. Allen, Joel D. Allen School of Biological Sciences, University of Southampton, Southampton, UK Contribution: Resources (supporting), Writing - review & editing (supporting)Search for more papers by this authorYasunori Watanabe, Yasunori Watanabe Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, Oxford, UK Contribution: Resources (supporting), Writing - review & editing (supporting)Search for more papers by this authorMargaret Goodall, Margaret Goodall Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK Contribution: Investigation (supporting), Resources (equal)Search for more papers by this authorBenjamin E. Willcox, Benjamin E. Willcox Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK Contribution: Resources (lead), Writing - review & editing (supporting)Search for more papers by this authorCarrie R. Willcox, Carrie R. Willcox Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK Contribution: Resources (lead), Writing - review & editing (supporting)Search for more papers by this authorMahboob Salim, Mahboob Salim Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK Contribution: Resources (lead), Writing - review & editing (supporting)Search for more papers by this authorDavid C. Wraith, David C. Wraith Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK Contribution: Formal analysis (supporting), Writing - review & editing (supporting)Search for more papers by this authorTonny V. Veenith, Tonny V. Veenith Department of Critical Care Medicine, University Hospitals Birmingham NHS Trust, Birmingham, UK Contribution: Resources (supporting), Writing - review & editing (supporting)Search for more papers by this authorEleni Syrimi, Eleni Syrimi Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK Contribution: Data curation (supporting), Resources (supporting)Search for more papers by this authorMark T. Drayson, Mark T. Drayson Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK Contribution: Data curation (supporting), Formal analysis (supporting), Writing - review & editing (supporting)Search for more papers by this authorDeepthi Jyothish, Deepthi Jyothish Department of General Paediatrics, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK Contribution: Resources (supporting), Writing - review & editing (supporting)Search for more papers by this authorEslam Al-Abadi, Eslam Al-Abadi Birmingham Clinical Trials Unit, University of Birmingham, Birmingham, UK Childhood Arthritis and Rheumatic Diseases Unit, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK Contribution: Resources (supporting), Writing - review & editing (supporting)Search for more papers by this authorAshish Chikermane, Ashish Chikermane Department of Cardiology, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK Contribution: Resources (supporting), Writing - review & editing (supporting)Search for more papers by this authorSteven B. Welch, Steven B. Welch Department of Paediatrics, Birmingham Chest Clinic and Heartlands Hospital, University Hospitals Birmingham, Birmingham, UK Contribution: Resources (supporting), Writing - review & editing (supporting)Search for more papers by this authorKavitha Masilamani, Kavitha Masilamani Department of General Paediatrics, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK Contribution: Resources (supporting), Writing - review & editing (supporting)Search for more papers by this authorScott Hackett, Scott Hackett West Midlands Immunodeficiency Centre, Heartlands Hospital, University Hospitals Birmingham, Birmingham, UK Contribution: Resources (supporting), Writing - review & editing (supporting)Search for more papers by this authorMax Crispin, Max Crispin School of Biological Sciences, University of Southampton, Southampton, UK Contribution: Resources (lead), Writing - review & editing (equal)Search for more papers by this authorBarnaby R. Scholefield, Corresponding Author Barnaby R. Scholefield [email protected] Paediatric Intensive Care Unit, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK Correspondence Alex G. Richter, Adam F. Cunningham, Institute of Immunology and Immunotherapy, University of Birmingham, B15 2TT Birmingham, UK. Emails: [email protected] (AGR); [email protected] (AFC) Barnaby R. Scholefield, Paediatric Intensive Care Unit, Birmingham Women's and Children's NHS Foundation Trust, B4 6NH Birmingham, UK. Email: [email protected] Contribution: Conceptualization (equal), Data curation (equal), Formal analysis (equal), Resources (equal), Writing - original draft (equal), Writing - review & editing (equal)Search for more papers by this authorAdam F. Cunningham, Corresponding Author Adam F. Cunningham [email protected] Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK Correspondence Alex G. Richter, Adam F. Cunningham, Institute of Immunology and Immunotherapy, University of Birmingham, B15 2TT Birmingham, UK. Emails: [email protected] (AGR); [email protected] (AFC) Barnaby R. Scholefield, Paediatric Intensive Care Unit, Birmingham Women's and Children's NHS Foundation Trust, B4 6NH Birmingham, UK. Email: [email protected] Contribution: Conceptualization (equal), Formal analysis (equal), Supervision (equal), Writing - original draft (equal), Writing - review & editing (equal)Search for more papers by this authorAlex G. Richter, Corresponding Author Alex G. Richter [email protected] Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK Correspondence Alex G. Richter, Adam F. Cunningham, Institute of Immunology and Immunotherapy, University of Birmingham, B15 2TT Birmingham, UK. Emails: [email protected] (AGR); [email protected] (AFC) Barnaby R. Scholefield, Paediatric Intensive Care Unit, Birmingham Women's and Children's NHS Foundation Trust, B4 6NH Birmingham, UK. Email: [email protected] Contribution: Conceptualization (equal), Supervision (equal), Writing - original draft (equal), Writing - review & editing (equal)Search for more papers by this author First published: 16 March 2021 https://doi.org/10.1111/pai.13504Citations: 9 Perez-Toledo, Faustini and Jossi these authors contributed equally. Scholefield, Cunningham, and Richter Joint senior authors. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES 1Ludvigsson JF. Systematic review of COVID-19 in children shows milder cases and a better prognosis than adults. Acta paediatr. 2020; 109(6): 1088-1095. 10.1111/apa.15270 CASPubMedWeb of Science®Google Scholar 2Riphagen S, Gomez X, Gonzalez-Martinez C, Wilkinson N, Theocharis P. Hyperinflammatory shock in children during COVID-19 pandemic. 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