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Management of anaphylaxis due to COVID‐19 vaccines in the elderly

2021; Wiley; Volume: 76; Issue: 10 Linguagem: Inglês

10.1111/all.14838

1398-9995

Jean Bousquet, Ioana Agache, Hubert Blain, Marek Jutel, Maria Teresa Ventura, Margitta Worm, Stefano Del Giacco, Athanasios Benetos, Beatrice M Bilò, Heather J. Zar, Amir Hamzah Abdul Latiff, Mona Al‐Ahmad, Elizabeth Angier, Isabella Annesi‐Maesano, Marina Atanasković‐Marković, Claus Bachert, A. Barbaud, Anna Bedbrook, Kazi Saifuddin Bennoor, Camelia Elena Berghea, Carsten Bindslev‐Jensen, С. Бонини, Sinthia Bosnic‐Anticevich, Knut Brockow, Luisa Brussino, Paulo Augusto Moreira Camargos, Giorgio Walter Canonica, Victòria Cardona, Pedro Martins, Ana Carriazo, Thomas B. Casale, Jean‐Christoph Caubet, Lorenzo Cecchi, Antonio Cherubini, George Christoff, Derek K. Chu, Álvaro A. Cruz, D Dokic, Yehia El‐Gamal, Motohiro Ebisawa, Bernadette Eberlein, John Farrell, Montserrat Fernández‐Rivas, Wytske J. Fokkens, João Fonseca, Yadong Gao, G. Gavazzi, Radosław Gawlik, Aslı Gelincik, Bilun Gemicioğlu, Maia Gotua, Olivier Guérin, Tari Haahtela, Karin Hoffmann‐Sommergruber, Hans Jürgen Hoffmann, Maja A. Hofmann, M Hrubiško, Maddalena Illario, Carla Irani, Zhanat Ispayeva, Juan Carlos Ivancevich, Kaja Julge, Ігор Петрович Кайдашев, Musa Khaitov, Edward F. Knol, Helga Kraxner, Piotr Kuna, Violeta Kvedarienė, Antti Lauerma, Lan Le, Vincent Le Moing, Michael Levin, Renaud Louis, Olga Lourenço, Vera Mahler, Finbarr C. Martin, Andrea Matucci, Branislava Milenković, Stéphanie Miot, Emma Montella, Mário Morais‐Almeida, Charlotte G. Mørtz, Joaquim Mullol, Leyla S. Namazova-Baranova, Hugo Neffen, K Nékám, Marek Niedoszytko, Mikaëla Odemyr, Robyn E. O’Hehir, Yoshitaka Okamoto, Markus Ollert, Óscar Palomares, Nikolaos G. Papadopoulos, Petr Panzner, Giovanni Passalacqua, Vincenzo Patella, Mirko Petrović, Oliver Pfaar, N. Pham‐Thi, Davor Plavec, Todor A. Popov, Marysia T. Recto, Frederico S. Regateiro, Jacques Reynes, R Roller-Winsberger, Yves Rolland, Antonino Romano, Carmen Rondón, Menachem Rottem, Philip W. Rouadi, Nathalie Salles, Bolesław Samoliński, Alexandra F. Santos, Faradiba S Sarquis, J. Sastre, Jos M. G. A. Schols, Nicola Scichilone, Anna Šedivá, Mohamed H. Shamji, Aziz Sheikh, Isabel Skypala, Sylwia Smolińska, Milena Sokołowska, Bernardo Sousa‐Pinto, Milan Sova, Rafaël Stelmach, Gunter J. Sturm, Charlotte Suppli Ulrik, Ana Todo‐Bom, Sanna Toppila‐Salmi, Ioanna Tsiligianni, Marı́a José Torres, Eva Untersmayr, Marilyn Urrutia Pereira, Arūnas Valiulis, Joana Vitte, Alessandra Vultaggio, Dana Wallace, Jolanta Walusiak‐Skorupa, De‐yun Wang, Susan Waserman, Arzu Yorgancıoğlu, Osman Yusuf, Mario Zernotti, Mihaela Zidarn, Tomás Chivato, Cezmi A. Akdiş, Torsten Zuberbier, Ludger Klimek,

Drug-Induced Adverse Reactions

Older adults, especially men and/or those with diabetes, hypertension, and/or obesity, are prone to severe COVID-19. In some countries, older adults, particularly those residing in nursing homes, have been prioritized to receive COVID-19 vaccines due to high risk of death. In very rare instances, the COVID-19 vaccines can induce anaphylaxis, and the management of anaphylaxis in older people should be considered carefully. An ARIA-EAACI-EuGMS (Allergic Rhinitis and its Impact on Asthma, European Academy of Allergy and Clinical Immunology, and European Geriatric Medicine Society) Working Group has proposed some recommendations for older adults receiving the COVID-19 vaccines. Anaphylaxis to COVID-19 vaccines is extremely rare (from 1 per 100,000 to 5 per million injections). Symptoms are similar in younger and older adults but they tend to be more severe in the older patients. Adrenaline is the mainstay treatment and should be readily available. A flowchart is proposed to manage anaphylaxis in the older patients.