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Torsional stress induces left-handed helical stretches in DNA of natural base sequence: circular dichroism and antibody binding.

1983; Springer Nature; Volume: 2; Issue: 9 Linguagem: Inglês

10.1002/j.1460-2075.1983.tb01619.x

1460-2075

E. Di Capua, Andrzej Stasiak, T. Köller, S. Brahms, R. Thomae, Fritz M. Pohl,

Bacteriophages and microbial interactions

Research Article1 September 1983free access Torsional stress induces left-handed helical stretches in DNA of natural base sequence: circular dichroism and antibody binding. E. Di Capua E. Di Capua Institut für Zellbiologie, ETH, Hönggerberg, Zürich, Switzerland. Search for more papers by this author A. Stasiak A. Stasiak Institut für Zellbiologie, ETH, Hönggerberg, Zürich, Switzerland. Search for more papers by this author T. Koller T. Koller Institut für Zellbiologie, ETH, Hönggerberg, Zürich, Switzerland. Search for more papers by this author S. Brahms S. Brahms Institut für Zellbiologie, ETH, Hönggerberg, Zürich, Switzerland. Search for more papers by this author R. Thomae R. Thomae Institut für Zellbiologie, ETH, Hönggerberg, Zürich, Switzerland. Search for more papers by this author F.M. Pohl F.M. Pohl Institut für Zellbiologie, ETH, Hönggerberg, Zürich, Switzerland. Search for more papers by this author E. Di Capua E. Di Capua Institut für Zellbiologie, ETH, Hönggerberg, Zürich, Switzerland. Search for more papers by this author A. Stasiak A. Stasiak Institut für Zellbiologie, ETH, Hönggerberg, Zürich, Switzerland. Search for more papers by this author T. Koller T. Koller Institut für Zellbiologie, ETH, Hönggerberg, Zürich, Switzerland. Search for more papers by this author S. Brahms S. Brahms Institut für Zellbiologie, ETH, Hönggerberg, Zürich, Switzerland. Search for more papers by this author R. Thomae R. Thomae Institut für Zellbiologie, ETH, Hönggerberg, Zürich, Switzerland. Search for more papers by this author F.M. Pohl F.M. Pohl Institut für Zellbiologie, ETH, Hönggerberg, Zürich, Switzerland. Search for more papers by this author Author Information E. Di Capua1, A. Stasiak1, T. Koller1, S. Brahms1, R. Thomae1 and F.M. Pohl1 1Institut für Zellbiologie, ETH, Hönggerberg, Zürich, Switzerland. The EMBO Journal (1983)2:1531-1535https://doi.org/10.1002/j.1460-2075.1983.tb01619.x PDFDownload PDF of article text and main figures. ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InMendeleyWechatReddit Figures & Info Above a threshold of torsional stress, the c.d. spectrum of covalently closed circular DNA of natural base sequence acquires a Z-like contribution and antibodies raised against Z-DNA are bound. Mapping of the antibody binding sites by electron microscopy reveals sites which correlate with stretches enriched in alternating purine-pyrimidine sequences and GC base pairs. Previous ArticleNext Article Volume 2Issue 91 September 1983In this issue RelatedDetailsLoading ...