Produção Nacional
Revisado por pares
Effect of Training-Detraining Phases of Multicomponent Exercises and BCAA Supplementation on Inflammatory Markers and Albumin Levels in Frail Older Persons
2021; Multidisciplinary Digital Publishing Institute; Volume: 13; Issue: 4 Linguagem: Inglês
10.3390/nu13041106
ISSN2072-6643
AutoresAdriana Caldo‐Silva, Guilherme Eustáquio Furtado, Matheus Uba Chupel, André Luís Lacerda Bachi, Marcelo P. Barros, Rafael Santos Neves, Emanuele Marzetti, Alain Massart, Ana Teixeira,
Tópico(s)Frailty in Older Adults
ResumoNowadays, it is accepted that the regular practice of exercise and branched-chain amino acids supplementation (BCAAs) can benefit the immune responses in older persons, prevent the occurrence of physical frailty (PF), cognitive decline, and aging-related comorbidities. However, the impact of their combination (as non-pharmacological interventions) in albumin and the inflammatory markers is not fully understood. Therefore, we investigated the effect of a 40-week multifactorial intervention [MIP, multicomponent exercise (ME) associated or not with BCAAs] on plasma levels of inflammatory markers and albumin in frail older persons (≥75 years old) living at residential care homes (RCH). This study consisted of a prospective, naturalistic, controlled clinical trial with four arms of multifactorial and experimental (interventions-wahshout-interventions) design. The intervention groups were ME + BCAAs (
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