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BIBTEX RIS

Malignant Phyllodes Tumor of the Breast: A Practice Review

2021; PAGEPress (Italy); Volume: 11; Issue: 2 Linguagem: Inglês

10.3390/clinpract11020030

2039-7283

Â. Fêde, Ronaldo Pereira Souza, Mauricio Doi, Marina De Brot, Cynthia Aparecida Bueno de Toledo Osório, Guilherme Rocha Melo Gondim, José Cláudio Casali da Rocha, Rima Jbili, Almir Galvão Vieira Bitencourt, Juliana Alves de Souza, Rafael Caparica Bitton, Fabiana Baroni Alves Makdissi, Solange Moraes Sanches,

Salivary Gland Tumors Diagnosis and Treatment

Introduction: Phyllodes tumor (PT) of the breast, particularly malignant phyllodes tumor (mPT), is a rare fibroepithelial neoplasm. A complex diagnosis is based on pathologic, radiologic, and clinical findings, with controversies about what is the best therapeutic strategy. Objective: Our objective was to provide an overview of the clinical, pathologic, and therapeutic aspects of this rare tumor. Conclusions: mPT is a rare presentation of breast cancer and a challenge in clinical practice. A multidisciplinary approach should take into account some aspects like pathogenic mutations and hereditary syndromes. Oncologic surgery is the fundamental approach, and the use of adjuvant therapies is still controversial due to the lack of clinical trials. Treatment recommendations should be individualized according to patient risk and preferences. Prospective studies are fundamental to clarifying the best treatment for these tumors.