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SARS-CoV-2 genome-wide T cell epitope mapping reveals immunodominance and substantial CD8 + T cell activation in COVID-19 patients

2021; American Association for the Advancement of Science; Volume: 6; Issue: 58 Linguagem: Inglês

10.1126/sciimmunol.abf7550

2470-9468

Sunil Kumar Saini, Ditte Stampe Hersby, Tripti Tamhane, Helle Rus Povlsen, Susana Patricia Amaya Hernandez, Morten Nielsen, Anne Ortved Gang, Sine Reker Hadrup,

vaccines and immunoinformatics approaches

T cells are important for effective viral clearance, elimination of virus-infected cells and long-term disease protection. To examine the full-spectrum of CD8