Artigo Produção Nacional

Oral Langerhans Cell Histiocytosis in Two Pediatric Patients.

2021; Volume: 88; Issue: 1 Linguagem: Inglês

ISSN

0022-0353

Autores

Alexandre de Freitas Caetano Guimarães, Gabriela Afonso de Souza, Thiago Moreira Pêssoa, Ruth Tramantoni Ramos, Marília Heffer Cantisano, Geraldo Oliveira Silva-Júnior,

Tópico(s)

Tumors and Oncological Cases

Resumo

We report two cases of Langerhans cell histiocytosis (LCH) in the oral cavity of children. An 11-month-old girl was referred for evaluation of a nodular and sessile lesion in the alveolar ridge covering the primary left mandibular central incisor. The second patient was a seven-year-old boy with an ulcerated lesion in the gingiva covered by necrotic areas, extending to the sulcus of the vestibule. The patients underwent incisional biopsies and histopathological exams showed a proliferation of Langerhans and eosinophil cells, suggesting a diagnosis of LCH, which was confirmed by positive immunohistochemical expression of S100 and CD1.

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