Artigo Acesso aberto Produção Nacional Revisado por pares

Long-Term Persistence of Serum-Specific Anti-Chikungunya IgM Antibody - A Case Series of Brazilian Patients

2021; Brazilian Society of Tropical Medicine; Volume: 54; Linguagem: Inglês

10.1590/0037-8682-0855-2020

ISSN

1678-9849

Autores

Denise Maria do Nascimento Costa, Maria Rosângela Cunha Duarte Coêlho, Pedro Alves da Cruz Gouveia, Luan Araújo Bezerra, Cláudia Diniz Lopes Marques, Ângela Luzia Branco Pinto Duarte, Lucila Maria Valente, Vera Magalhães,

Tópico(s)

Viral Infections and Outbreaks Research

Resumo

The persistence of serum-specific anti-chikungunya IgM antibodies (CHIKV-IgM) can vary after chikungunya fever (CHIK) infection. However, the factors related to its production are not yet known. We described a case series drawn up from data collected from 57 patients between 12 and 36 months after the acute phase of CHIK infection in Northeastern Brazil. CHIKV-IgM was detectable in 7/57 (12.3%) patients after 28.3 months of infection. No frequency differences in chronic musculoskeletal manifestations and underlying conditions were detected between patients with or without CHIKV-IgM. CHIKV-IgM was detected for up to 35 months in Brazilian patients after CHIK infection.

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