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BIBTEX RIS

Prolonged presence of replication‐competent SARS‐CoV‐2 in mildly symptomatic individuals: A report of two cases

2021; Wiley; Volume: 93; Issue: 9 Linguagem: Inglês

10.1002/jmv.27021

1096-9071

Maria Cássia Mendes-Corrêa, Fábio E. Leal, Lucy Santos Villas Boas, Steven S. Witkin, Anderson Vicente de Paula, Tânia Regina Tozetto‐Mendoza, Noely Evangelista Ferreira, Gislaine Curty, Pedro S. de Carvalho, Lewis Buss, Sílvia Figueiredo Costa, Flavia M. da Cunha Carvalho, Joyce T. Kawakami, Noemi Nosomi Taniwaki, Heuder Gustavo Oliveira Paião, João Carlos da Silva Bizário, Jaqueline Góes de Jesus, Éster Cerdeira Sabino, Camila Malta Romano, Regina Maura Zetone Grepan, Antônio Sesso,

COVID-19 Clinical Research Studies

It has been estimated that individuals with COVID-19 can shed replication-competent virus up to a maximum of 20 days after initiation of symptoms. The majority of studies that addressed this situation involved hospitalized individuals and those with severe disease. Studies to address the possible presence of SARS-CoV-2 during the different phases of COVID-19 disease in mildly infected individuals, and utilization of viral culture techniques to identify replication-competent viruses, have been limited. This report describes two patients with mild forms of the disease who shed replication-competent virus for 24 and 37 days, respectively, after symptom onset.