Granulomatosis eosinofílica con poliangeítis
2021; Elsevier BV; Volume: 10; Issue: 1 Linguagem: Inglês
10.24038/mgyf.2021.004
ISSN2254-5506
AutoresJavier Bustamante Odriozola, Álvaro Pérez Martín, Daniel Martínez Revuelta, Patricia Fierro, Matthew Domínguez Suárez, Nadia Huarachi Berne, Ana Isabel Rodríguez,
Tópico(s)Urticaria and Related Conditions
ResumoespanolLa granulomatosis eosinofilica con poliangeitis es un trastorno multisistemico caracterizado por rinosinusitis cronica, asma y eosinofilia prominente de sangre periferica. La clinica es muy variable; tienen principal predileccion por el pulmon y la piel, pero puede afectar tambien a otros organos. Para el diagnostico se emplean tanto criterios clinicos como analiticos. Existen multiples guias; la del American College of Rheumatology es la mas empleada. El tratamiento puede requerir del uso de corticoides y ciclofosfamida inicialmente; puede emplearse metotrexate, lefluonamida, azatioprina o terapias biologicas EnglishEosinophilic granulomatosis with polyangiitis is a multisystemic disorder characterized by chronic rhinosinusitis, asthma, and prominent eosinophilia of peripheral blood. The clinic is very variable having a main predilection for the lung and the skin but may also affect other organs. Both clinical and analytical criteria are used for the diagnosis. There are multiple guides, with the American College of Rheumatology (ACR) being the most widely used. Treatment may require the use of corticosteroids and cyclophosphamide initially, and methotrexate, lefluonamide, azathioprine, or biological therapies may be used.
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