
Post-traumatic stress disorder as a predictor for incident hypertension: a 3-year retrospective cohort study
2021; Cambridge University Press; Volume: 53; Issue: 1 Linguagem: Inglês
10.1017/s0033291721001227
ISSN1469-8978
AutoresVictoria Mendlowicz, Maria Luiza Garcia-Rosa, Márcio Gekker, Larissa Wermelinger, William Berger, Mariana Pires de Luz, Paulo Roberto Telles Pires-Dias, Carla Marques-Portela, Ivan Figueira, Mauro V. Mendlowicz,
Tópico(s)Healthcare professionals’ stress and burnout
ResumoThe goal of the present study was to investigate the association between PTSD and the onset of hypertension in previously normotensive individuals in a population living in the stressful environment of the urban slums while controlling for risk factors for cardiovascular disease (CVD).Participants were 320 normotensive individuals who lived in slums and were attending a family doctor program. Measurements included a questionnaire covering sociodemographic characteristics, clinical status and life habits, the Posttraumatic Stress Disorder Checklist - Civilian Version, and the Beck Depression Inventory. Incident hypertension was defined as the first occurrence at the follow-up review of the medical records of (1) systolic blood pressure of 140 mm Hg or higher or diastolic blood pressure of 90 mm Hg or higher, (2) the participant started taking antihypertensive medication, or (3) a new diagnosis of hypertension made by a physician. Differences in sociodemographic, clinical, and lifestyle characteristics between hypertensive and non-hypertensive individuals were compared using the χ2 and t tests. Multivariate Cox proportional hazards models were used to calculate hazard ratios (HR) and 95% confidence intervals (CI).Six variables - age, educational level, body mass, smoking, diabetes, and PTSD diagnosis - showed a statistically significant (p ≤ 0.20) association with the hypertensive status. In the Cox regression, only PTSD diagnosis was significantly associated with incident hypertension (multivariate HR = 1.94; 95% CI 1.11-3.40).The present findings highlight the importance of considering a diagnostic hypothesis of PTSD in the prevention and treatment of cardiovascular diseases.
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