Produção Nacional
Healthcare-Associated Infections on the ICU in 21 Brazilian Hospitals During the COVID-19 Pandemic
2021; RELX Group (Netherlands); Linguagem: Inglês
10.2139/ssrn.3796913
ISSN1556-5068
AutoresAna Paula Matos Porto, Igor C. Borges, Lewis Buss, Anna Machado, Bil Randerson Bassetti, Brunno César Batista Cocentino, Camila da Silva Bicalho, Cláudia Maria Dantas de Maio Carrilho, Cristhieni Rodrigues, Eudes Alves Simões Neto, Evelyne Santana Girão, Filipe Teixeira Piastrelli, Giovanna Sapienza, Glaucia Fernanda Varkulja, Karin Kolbe, Luciana Neves Passos, Patrícia Esteves, Pollyana Gitirana, Regia Damous Fontenele Feijó, Rosane Luiza Coutinho, Thaís Guimarães, Tiago Luiz Lagedo Ferraz, Anna S. Levin, Sílvia Figueiredo Costa, HAI COVID- Brazilian Task Force Group,
Tópico(s)Family and Patient Care in Intensive Care Units
ResumoBackground: The coronavirus disease 2019 (COVID-19) pandemic has caused a global health crisis and it might have affected healthcare-associated infections (HAI) prevention strategies. This study aims to evaluate the impact of the COVID-19 pandemic on HAI incidence in Brazilian ICUs.Methods: This ecological study compared adult patients admitted to the ICU from April through June 2020 (pandemic period) with the same period in 2019 (pre-pandemic period). We collected data from 21 hospitals from the three most populated Brazilian regions. The difference in microbiologically confirmed central line-associated bloodstream infection (CLABSI) and ventilator-associated pneumonia (VAP) incidence density, and the proportion of organisms that caused HAI between the pandemic and the pre-pandemic periods were compared in a pairwise analysis using the Wilcoxon signed rank sum test. Findings: We observed a significant increase in CLABSI incidence during the pandemic (2.81 [1.35 - 6.89] vs. 1.60 [0.44 - 4.20], p = 0.002). Overall, there was no difference in VAP incidence between the two periods, but there was an increase in VAP incidence in private hospitals during the pandemic (3.65 [1.42 - 6.57] vs. 2.54 [0 - 3.98], p = 0.033). In addition, there was a significant increase in the proportion of CLABSI caused by Enterococcus faecalis and candida species during the pandemic.Interpretation: There was an increase in CLABSI incidence in Brazilian hospitals during the COVID-19 pandemic. Additionally, we observed an increase in the proportion of CLABSI caused by E. faecalis and candida species in this period. Funding: None.Declaration of Interests: None. Ethics Approval Statement: The study protocol 77243517.8 was approved by the ethics committee of each participating hospital.
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