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Supercritical CO2 Extraction as a Tool to Isolate Anti-Inflammatory Sesquiterpene Lactones from Cichorium intybus L. Roots

2021; Multidisciplinary Digital Publishing Institute; Volume: 26; Issue: 9 Linguagem: Inglês

10.3390/molecules26092583

1433-1373

João P. Baixinho, José D. Anastácio, Viktoriya Ivasiv, Katarina Cankar, Dirk Bosch, Regina Menezes, Matthew de Roode, Cláudia Nunes dos Santos, Ana A. Matias, Naiara Fernández,

Natural product bioactivities and synthesis

. or chicory plants are a natural source of health-promoting compounds in the form of supplements such as inulin, as well as other bioactive compounds such as sesquiterpene lactones (SLs). After inulin extraction, chicory roots are considered waste, with most SLs not being harnessed. We developed and optimized a new strategy for SL extraction that can contribute to the conversion of chicory root waste into valuable products to be used in human health-promoting applications. In our work, rich fractions of SLs were recovered from chicory roots using supercritical CO