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BIBTEX RIS

Efficient synthesis of antiviral agent uprifosbuvir enabled by new synthetic methods

2021; Royal Society of Chemistry; Volume: 12; Issue: 26 Linguagem: Inglês

10.1039/d1sc01978c

ISSN

2041-6539

Autores

Artis Klapars, John Y. L. Chung, John Limanto, Ralph Calabria, Louis‐Charles Campeau, Kevin R. Campos, Wenyong Chen, Stephen M. Dalby, Tyler A. Davis, Daniel A. DiRocco, Alan M. Hyde, Amude M. Kassim, Mona Utne Larsen, Guiquan Liu, Peter E. Maligres, Aaron Moment, Feng Peng, Rebecca T. Ruck, Michael Shevlin, Bryon Simmons, Zhiguo J. Song, Lushi Tan, Timothy J. Wright, Susan L. Zultanski,

Tópico(s)

Hepatitis C virus research

Resumo

An efficient route to the HCV antiviral agent uprifosbuvir was developed in 5 steps from readily available uridine in 50% overall yield.

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