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BIBTEX RIS

Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants

2021; American Association for the Advancement of Science; Volume: 373; Issue: 6556 Linguagem: Inglês

10.1126/science.abh1139

ISSN

1095-9203

Autores

Meng Yuan, Deli Huang, Chang‐Chun D. Lee, Nicholas C. Wu, Abigail M. Jackson, Xueyong Zhu, Hejun Liu, Linghang Peng, Marit J. van Gils, Rogier W. Sanders, Dennis R. Burton, S. Momsen Reincke, Harald Prüß, Jakob Kreye, David Nemazee, Andrew B. Ward, Ian A. Wilson,

Tópico(s)

vaccines and immunoinformatics approaches

Resumo

Neutralizing antibodies (nAbs) elicited against the receptor binding site (RBS) of the spike protein of wild-type severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are generally less effective against recent variants of concern. RBS residues Glu

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